产品货号：
Z17449
中文名称：
HAAO抗体
英文名称：
Anti-HAAO Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HAAO Antibody |
| 指标别名 | 3 HAO;HAAO;HAD;HAO |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | HAAO |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | HAAO antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human HAAO.The immunogen is located within amino acids 30 - 80 of HAAO. |
| 计算分子量 | 33kDa |
| 成分 | HAAO Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | HAAO Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | HAAO (3-Hydroxyanthranilate 3,4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron.It is widely distributed in peripheral organs,such as liver and kidney,and is present in low amounts in the central nervous system.This enzyme participates in tryptophan metabolism.It employs one cofactor,iron.HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid.QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors.Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders.HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.Furthermore,recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer. |
| Uniprot ID | P46952 |
| 基因名全称 | 3-hydroxyanthranilate 3,4-dioxygenase |
| 蛋白名全称 | 3-hydroxyanthranilate 3,4-dioxygenase |
| 推荐稀释比 | HAAO antibody can be used for detection of HAAO by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索：HAAO抗体，HAAO多抗，Anti-HAAO Antibody